is statin effective on treatment of hepatitis c genotype 1?
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چکیده
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منابع مشابه
Statin efficacy in the treatment of hepatitis C genotype I
BACKGROUND Lipid metabolism is one of the hepatitis C virus (HCV) life cycle steps. Statins can reduce cholesterol level and finally can decrease HCV replication. Thus, we assessed the effect of Statins in combination with standard antiviral treatment on hyperlipidemic genotype I HCV infected patients. MATERIALS AND METHODS This study was a prospective clinical trial. 40 patients were selecte...
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The authors have stated that pegylated (peg)-interferon therapy is cost-effective as compared to conventional interferon therapy. Clinical studies including this one show that the conventional interferon therapy is quite effective and efficacious for the treatment of genotype-3 chronic hepatitis C patients and the side effects are nearly the same with both treatments. The number of patients tre...
متن کاملBudget impact analysis of boceprevir and telaprevir for the treatment of hepatitis C genotype 1 infection
BACKGROUND Boceprevir and telaprevir have recently showed dramatically better treatment outcomes than conventional PEGylated interferon plus ribavirin for the treatment of hepatitis C virus genotype 1, but the average cost per patient is unknown. METHODS In the UK context, we performed a budget impact analysis to estimate the average per patient cost of adding boceprevir or telaprevir to PEGy...
متن کاملMixed Genotype Hepatitis C Infections and Implications for Treatment
The recently licensed direct-acting antivirals (DAAs) boceprevir and telaprevir used to treat hepatitis C virus (HCV) infection act in a genotype-specific manner. The potential outcome of DAA treatment regimes on mixed HCV infections, consisting of concurrent infection with more than one HCV genotype, has not been considered. Standard genotyping methods are only capable of identifying the domin...
متن کاملReal-world effectiveness of ledipasvir/sofosbuvir in 4,365 treatment-naive, genotype 1 hepatitis C-infected patients.
UNLABELLED Real-world effectiveness data are needed to inform hepatitis C virus (HCV) treatment decisions. The uptake of ledipasvir/sofosbuvir (LDV/SOF) regimens across health care settings has been rapid, but variations often occur in clinical practice. The aim of this study was to assess sustained virologic response (SVR) of LDV/SOF±ribavirin (RBV) in routine medical practice. This observatio...
متن کاملViral kinetics during the first month of treatment in patients with genotype 1 chronic hepatitis C.
OBJECTIVE to identify predictive factors of response to pegylated interferon alpha-2b and ribavirin in patients with genotype 1 chronic hepatitis C. Viral kinetics were studied in weeks 2 and 4. METHODS a prospective and consecutive study of patients with genotype 1 chronic hepatitis C referred to our Hepatology Clinic between January 2004 and October 2006 for antiviral treatment. Baseline da...
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عنوان ژورنال:
journal of research in medical sciencesجلد ۱۹، شماره ۳، صفحات ۰-۰
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